Olefin metathesis in multiblock copolymer synthesis

• Maria L. Gringolts,
• Yulia I. Denisova,
• Eugene Sh. Finkelshtein and
• Yaroslav V. Kudryavtsev

Beilstein J. Org. Chem. 2019, 15, 218–235, doi:10.3762/bjoc.15.21

• the nanoparticles were formed by a ABCBA pentablock copolymer. In this polymer A stands for hydrophilic oligo(ethylene glycol) (OEG)-grafted polynorbornene possessing stealth-like and antifouling properties that are useful for in vivo applications. The B block is formed by polynorbornene

Self-assemblies of γ-CDs with pentablock copolymers PMA-PPO-PEO-PPO-PMA and endcapping via atom transfer radical polymerization of 2-methacryloyloxyethyl phosphorylcholine

• Jing Lin,
• Tao Kong,
• Lin Ye,
• Ai-ying Zhang and
• Zeng-guo Feng

Beilstein J. Org. Chem. 2015, 11, 2267–2277, doi:10.3762/bjoc.11.247

• pentablock copolymer chain to generate single-chain-stranded loose-fit PPRs and showed no characteristic channel-like crystal structure. All the self-assembly processes of the pentablock copolymers resulted in the formation of hydrogels. After endcapping via in situ ATRP of 2-methacryloyloxyethyl

• -chain-stranded; pentablock copolymer; poly(pseudorotaxane); polyrotaxane; single-chain-stranded; Introduction Cyclodextrins (CDs) are a series of macrocyclic molecules composed of 6, 7, or 8 (α-, β-, and γ-CD, respectively) glucopyranose units. Their hydrophilic surface and hydrophobic inner cavity

• double-chain-stranded tight-fit PPRs [17]. In the WXRD patterns of all the PPRs, the disappearance of two prominent peaks at 19.2° and 23.3° of the central PEO segment in the pentablock copolymer PEP100M verified their self-assembly with γ-CDs. Surprisingly, these PPRs presented varying diffraction

Loose-fit polypseudorotaxanes constructed from γ-CDs and PHEMA-PPG-PEG-PPG-PHEMA

• Tao Kong,
• Lin Ye,
• Ai-ying Zhang and
• Zeng-guo Feng

Beilstein J. Org. Chem. 2014, 10, 2461–2469, doi:10.3762/bjoc.10.257

• Tao Kong Lin Ye Ai-ying Zhang Zeng-guo Feng School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China 10.3762/bjoc.10.257 Abstract A pentablock copolymer was prepared via the atom transfer radical polymerization of 2-hydroxyethyl methacrylate (HEMA

• ) initiated by 2-bromoisobutyryl end-capped PPO-PEO-PPO as a macroinitiator in DMF. Attaching PHEMA blocks altered the self-assembly process of the pentablock copolymer with γ-CDs in aqueous solution. Before attaching the PHEMA, the macroinitiator was preferentially bent to pass through the inner cavity of γ

• -CDs to give rise to tight-fit double-chain stranded polypseudorotaxanes (PPRs). After attaching the PHEMA, the resulting pentablock copolymer was single-chain stranded into the interior of γ-CDs to form more stable, loose-fit PPRs. The results of 1H NMR, WXRD, DSC, TGA, 13C CP/MAS NMR and FTIR